منابع مشابه
Statins and cerebral vasomotor reactivity: implications for a new therapy?
See related article, pages 2540-2545. Animal models have shown that cholesterol-lowering therapy with 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitors (commonly called statins) may augment absolute cerebral blood flow (CBF) by enhancing nitric oxide synthase (eNOS).1 Statins upregulate type III endothelial eNOS in thrombocytes, decrease platelet activation, and protect from cerebral i...
متن کاملCerebral hypercapnia-induced vasomotor reactivity in migraine with and without aura: a case-control study
Abstract Background: Dysfunction of the autonomic nervous system has long been a subject of considerable debate and a large number of studies have disclosed contradictory results. The aim of this study was to compare cerebral vasomotor reactivity in migraine with aura (MWA) patients with migraine without aura (MWO) ones. Methods: Ten MWA patients (7 females and 3 males mean age: 39.70 years, S...
متن کاملCortical neuromodulation modifies cerebral vasomotor reactivity.
BACKGROUND AND PURPOSE Cerebral vasomotor reactivity (VMR) is a capability of cerebral vessels to dilate in response to hypercapnia. Transcranial direct current stimulation (tDCS) effects on cerebral hemodynamics have been poorly studied. METHODS Ten healthy subjects underwent anodal/cathodal tDCS on the left motor cortex. Before and after tDCS, VMR assessment by transcranial Doppler and an e...
متن کاملCerebral vasomotor reactivity and risk of mortality: the Rotterdam Study.
BACKGROUND AND PURPOSE Accumulating vascular pathology in cerebral arteries leads to impaired cerebral vasomotor reactivity. In turn, impaired cerebral vasomotor reactivity is a risk factor for stroke in clinical populations. It remains unclear whether impaired cerebral vasomotor reactivity also reflects more systemic vascular damage. We investigated whether cerebral vasomotor reactivity is ass...
متن کاملCerebral vasomotor reactivity in normotensive and spontaneously hypertensive rats.
Intravenously injected metaraminol induced a larger blood pressure increase in spontaneously hypertensive rats (SHR) than in normotensive controls (NR) when the pressure was raised from the same starting level. Cerebral blood flow (CBF) response in NR was either perfect autoregulation, partial autoregulation or "break-through." When present, the autoregulatory response was very rapid, i.e. the ...
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ژورنال
عنوان ژورنال: Stroke
سال: 2006
ISSN: 0039-2499,1524-4628
DOI: 10.1161/01.str.0000239656.59618.d4